What is the Endocannabinoid System?

The Endocannabinoid System

The endocannabinoid system is responsible for controlling many vital functions in the body due to its presence in the central nervous system. It influences critical processes such as eating, sleeping, learning, processing emotions, immune and inflammatory responses, memory, as well as pain and temperature control.

As far as we know right now, there are two different types of cannabinoid receptors that are found closely packed in our brains and bodies. The CB1 receptors are primarily found in the brain, whereas the CB2 receptors are primarily found in immune tissues.

In the Brain

The CB1 receptors and naturally-occurring cannabinoid molecules in the brain allow for immediate adjustments and fine-tuning of the activity and levels of other neurotransmitters. This can help adjust anything from alertness to hunger to the body’s internal temperature.

When there are disorders with CB1 receptors, these can manifest in alcohol or drug addiction-related behaviors, mental health disorders like anxiety, depression, bipolar, or even schizophrenia, and motor dysfunction.

The CB2 receptors are primarily present in immune cells and tissues, and, under normal conditions, to a very limited extent in the brain. However, after inflammation or injury, CB2 receptors can be introduced into the microglia in the central nervous system (CNS).

In healthy human brains, microglia make up 0.5-16.6% of the total cells depending on the region of the brain in question. Recent studies suggest that they constantly move, searching for infections and inflammation, which CB2 receptors are thought to be adept at dealing with as well.

In the Immune System

As was mentioned above, CB2 receptors are primarily located in immune cells and tissues. They are critical in dealing with inflammatory responses in the brain, as well as throughout the body. In fact, in animal studies, mice who did not have the CB2 receptor have an enhanced inflammatory response compared to other mice when introduced to the same conditions.


The endocannabinoid system also regulates the body’s production and release of lymphocytes, which is thought to be something the CB2 receptors can control.

Lymphocytes are a vital type of immune cell. They’re white blood cells that are designed to destroy other  

cells and foreign bodies that have been determined to be harmful to our bodies. There are two different types of lymphocytes: B-cells, which fight off bacteria, viruses, and other toxins, and T-cells, which destroy our own cells that have either been taken over by a virus or that have become cancerous.

In the Gut

People have known about the endocannabinoid system’s benefits for gut health for centuries, if not millenia, but we are just now starting to be able to learn and test the science behind it.

We are now learning just how critical of a role that CB2 receptors play in gut health. Our intestines are constantly exposed to a variety of “insults,” but not all of them are pathogens that must be destroyed, like food particles and friendly flora. This is where the endocannabinoid system comes in.

Additionally, the CB2 receptors are believed to play a part in regulating pain in inflammatory bowel conditions like Chron’s and IBD. They can also help with making sure our intestines contract properly, or in a dysfunctional state, they can cause contractions to happen either too frequently or too infrequently.

How Can The Good Doctor Wellness Products Help?

The Good Doctor Wellness CBD products are able to bind to both CB1 and CB2 receptors to provide you with a full spectrum of potential benefits. Additionally, because all of The Good Doctor Wellness CBD products are lab-tested, non-GMO, vegan, and organic, there are no questions when it comes to what you’re getting and ingesting.